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Opioid Tolerance & Pain Management

  • Gulati, S., Briyal, S., Jones, S., Bhalla, S., and Gulati, A. (2017) Attenuation of opioid tolerance by ETB receptor agonist, IRL-1620, is independent of an accompanied decrease in nerve growth factor in mice. Heliyon 3, e00317
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  • Bhalla, S., Andurkar, S. V., and Gulati, A. (2016) Neurobiology of opioid withdrawal: Role of the endothelin system. Life Sci 159, 34-42
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  • Devarapalli, M., Leonard, M., Briyal, S., Stefanov, G., Puppala, B. L., Schweig, L., and Gulati, A. (2016) Prenatal Oxycodone Exposure Alters CNS Endothelin Receptor Expression in Neonatal Rats. Drug Res (Stuttg) 66, 246-250
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  • Bhalla, S., Pais, G., Tapia, M., and Gulati, A. (2015) Endothelin ETA receptor antagonist reverses naloxone-precipitated opioid withdrawal in mice. Can J Physiol Pharmacol 93, 935-944
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  • Bhalla, S., Zhang, Z., Patterson, N., and Gulati, A. (2010) Effect of endothelin-A receptor antagonist on mu, delta and kappa opioid receptor-mediated antinociception in mice. Eur J Pharmacol 635, 62-71
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  • Gulati, A., Bhalla, S., Matwyshyn, G., Zhang, Z., and Andurkar, S. V. (2009) Determination of adrenergic and imidazoline receptor involvement in augmentation of morphine and oxycodone analgesia by clonidine and BMS182874. Pharmacology 83, 45-58
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  • Matwyshyn, G. A., Bhalla, S., and Gulati, A. (2006) Endothelin ETA receptor blockade potentiates morphine analgesia but does not affect gastrointestinal transit in mice. Eur J Pharmacol 543, 48-53
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  • Puppala, B. L., Bhalla, S., Matwyshyn, G., and Gulati, A. (2006) Involvement of central endothelin receptors in neonatal morphine withdrawal. Exp Biol Med (Maywood) 231, 1157-1160
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  • Bhalla, S., Ciaccio, N., Wang, Z. J., and Gulati, A. (2006) Involvement of endothelin in morphine tolerance in neuroblastoma (SH-SY5Y) cells. Exp Biol Med (Maywood) 231, 1152-1156
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  • Puppala, B. L., Bhalla, S., Matwyshyn, G., and Gulati, A. (2006) Role of endothelin (ETA) receptors in neonatal morphine withdrawal. Peptides 27, 1514-1519
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  • Bhalla, S., Matwyshyn, G., and Gulati, A. (2005) Morphine tolerance does not develop in mice treated with endothelin-A receptor antagonists. Brain Res 1064, 126-135
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  • Puppala, B. L., Matwyshyn, G., Bhalla, S., and Gulati, A. (2004) Role of endothelin in neonatal morphine tolerance. J Cardiovasc Pharmacol 44 Suppl 1, S383-385
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  • Gulati, A., Bhalla, S., and Matwyshyn, G. (2004) A novel combination of opiates and endothelin antagonists to manage pain without any tolerance development. J Cardiovasc Pharmacol 44 Suppl 1, S129-131
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  • Puppala, B. L., Matwyshyn, G., Bhalla, S., and Gulati, A. (2004) Evidence that morphine tolerance may be regulated by endothelin in the neonatal rat. Biol Neonate 86, 138-144
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  • Bhalla, S., Matwyshyn, G., and Gulati, A. (2004) Central endothelin-B receptor stimulation does not affect morphine analgesia in rats. Pharmacology 72, 20-25
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  • Bhalla, S., Matwyshyn, G., and Gulati, A. (2002) Potentiation of morphine analgesia by BQ123, an endothelin antagonist. Peptides 23, 1837-1845
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  • Bhalla, S., Matwyshyn, G., and Gulati, A. (2003) Endothelin receptor antagonists restore morphine analgesia in morphine tolerant rats. Peptides 24, 553-56
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